ea0011oc11 | Steroids and reproductive endocrinology | ECE2006
Beuschlein F
, Heshkovitz L
, Klammer S
, Lichtenauer U
, Shapiro I
, Krup M
, Weinstein Y
20alpha-hydroxysteroid dehydrogenase (20αHSD) has been initially characterized as a progesterone metabolizing enzyme of the ovary mandatory for the final reduction of progesterone blood levels before parturition. As the exact zonal distribution and regulation of adrenal 20αHSD has not been defined, adrenal 20αHSD expression and activity was determined by western blotting, immunohistochemistry and enzymatic assays in wild type BALB/c mice of both genders at diffe...